First randomized controlled trial of home hospital model in the U.S. reports improvements in outcomes meaningful to health systems and patients 鈥� sets stage for transformation of acute care delivery

Boston, MA 鈥� The model of care 鈥� in which select patients receive hospital-level care for an acute illness from the comfort of their own home instead of in a traditional hospital 鈥� has become increasingly popular across the United States. A pilot study conducted by investigators at Brigham and Women鈥檚 Hospital indicated that the home hospital model has the potential to lower costs and improve care. Now, the results of the investigators鈥� randomized controlled trial with more patients strengthens the evidence, showing that home hospital care reduced cost, utilization, and readmissions while increasing physical activity compared with usual hospital care. Results are published in .

鈥淭his work cements the idea that, for the right patients, we can deliver hospital-level care outside of the four walls of the traditional hospital and provides more of the data we need to make home hospital care the standard of care in our country,鈥� said corresponding author , a physician and researcher in the Division of General Internal Medicine and Primary Care. 鈥淚t opens up so many exciting possibilities 鈥� it鈥檚 exciting for patients because it gives them the opportunity to be in a familiar setting, and it鈥檚 exciting for clinicians because we get to be with a patient in that person鈥檚 own surroundings. As a community-minded hospital, this is a way for us to bring excellent care to our community.鈥�

Levine and colleagues enrolled 91 adults into their trial. Each patient had been admitted via the emergency department at Brigham and Women鈥檚 Hospital or Brigham and Women鈥檚 Faulkner Hospital with a select acute condition 鈥� including infection, heart failure exacerbation, chronic obstructive pulmonary disease exacerbation and asthma exacerbation 鈥� and lived within five miles of the hospital. Patients were randomized to either stay at the hospital and receive standard care or receive care at home, which included nurse and physician home visits, intravenous medications, remote monitoring, video communication and point-of-care testing.

The team measured the total direct cost of care, including costs for nonphysician labor, supplies, medications and diagnostic tests. They found that for patients who received care at home, total costs were 38 percent lower than for control patients. Home hospital patients had fewer lab orders, used less imaging and had fewer consultations. The team also found that home hospital patients spent a smaller portion of their day sedentary or lying down and had lower readmission rates within 30 days than control patients. Because of the strength of its positive findings, the study was stopped early.

Levine notes that payment remains a challenge for the home hospital model, in part because most insurance companies do not yet recognize the home as a place where hospital-level care happens, although Brigham is making headway with insurers. With the conclusion of the trial, the Brigham is now increasing home hospital capacity to make it clinically available to more patients.

Levine and his colleagues are continuing to test and improve the home hospital model.

鈥淲e know there鈥檚 always more work to be done, and so we pride ourselves on being a continuous learning and innovation shop,鈥� he said. 鈥淲e鈥檙e now launching trials that include remote patient care, we鈥檙e adding artificial intelligence to home hospital care and we鈥檙e even exploring ways to bring home hospital care to rural settings. We鈥檒l continue to refine and spread this model so that even more patients can get home hospital care.鈥�

This work is supported by the Partners HealthCare Center for Population Health and internal departmental funds. Levine reports grants from Biofourmis outside the submitted work. A co-author reports consulting income from Verily, GreyBird Ventures, and Atlas5D outside the submitted work. A co-author reports grants from Mallinckrodt Pharmaceuticals and Portola Pharmaceuticals outside the submitted work.