Finding solutions for complex health problems requires the creativity of experts in a wide range of disciplines. The Division of Engineering in Medicine at Brigham and Women’s Hospital (BWH) brings together specialists in bioengineering, electrical engineering, computer science, chemistry, molecular and cancer biology, clinical medicine, physics, pharmacology, and nanotechnology to address some of the most challenging issues in medicine. The Division’s roots at BWH feature a long history of improving patient care that has resulted in more than 10 companies and 100 patents.
Today, the Division is focused on several key areas, including Functional and Regenerative Medicine and Project BME-HEAL (Biomedical Engineering for Health – Effective and Affordable for All). Our researchers are using new techniques in science and technology to impact how cells, tissues, and organs function and to optimize the delivery of life saving therapies. Examples include tissue engineering and 3D printing to address organ transplant rejection and shortage of organs available for transplantation; use of stem cells and other cellular therapies to treat autoimmune diseases, cancer, liver and kidney diseases; and the creation of nanoparticles to deliver targeted therapies for cancer and other serious diseases.
Cancer Cell-Cell and Cell-Matrix Interaction Center (CCIC)
The Cancer Cell-Cell and Cell-Matrix Interaction Center (CCIC)” at the Harvard Medical School-affiliated Massachusetts General Brigham (MGB) is setting up an “International Cytocapsular Tube (CCT)-Cancer Training Program (ICTP).” Institutes are invited to support individuals to attend the ICTP. The ICTP will provide comprehensive training related to cytocapsular tubes and cancer, including an atlas of the appearance of cytocapsular tubes and human native cancer, cytocapsular membranes, cancer metastasis in 3D CCT network highway systems, and CCT initiation and elongation mechanisms. Training will also be available in CCT imaging and image analysis and in collection of CCT material for characterization.
Accomplishments of our team members include:
- (Hadi Shafiee, PhD)
- Modeling Genetic Diseases in Mini-kidney Organoids (Joseph V. Bonventre, MD, PhD)
- Growing Artificial Human Micro-livers to Fight Infections (Sangeeta Bhatia, PhD)
- Inspiring Medical Innovations through Nature (Jeffrey Karp, PhD)
- Making Organs from Scratch (Ali Khademhosseini, PhD)
- Revealing Cancer Treatment Effectiveness in Real Time (Ashish A. Kulkarni, PhD)
- Getting Stem Cells to Sites of Disease and Damage (Oren Levy, PhD)
- Catching Cancer Cells in Vulnerable State (Shiladitya Sengupta, PhD)
Related Links
