The purpose of BICOR is to fulfill the need for radiotracers for research staff and clinicians. The facility includes a medical cyclotron, radiotracer processing facilities which meet the requirements of current good manufacturing practices (cGMP), a radiopharmacy, a micro PET/CT lab, and various support laboratories.
The cyclotron produces PET isotopes, C-11, N-13, O-15, and F-18 from which a variety of compounds are prepared for both pre-clinical and human use.
Compounds with FDA approved clinical applications
Compounds currently available for research use in humans
- 18-F AraG (Proprietary - Cellsight)
Compounds currently available for pre-clinical use
- (High concentration for prolonged preclinical protocols)
- (GE Healthcare proprietary compound)
- (GE Healthcare proprietary compound)
- 18F-Fluoride (Available as radiochemical grade only)
Compounds currently under development or consideration
- (novel radiolabel)
- 18F-VHH (novel radiolabel)
- 18F-Flurodopa
- 18-F MMPi
- 18-F 3F4AP
- 18-F mFBG
Compounds with previous development & manufacturing history at BICOR
- (Pending IND)
- 18F-AV1451 (AVID Proprietary Compound for TAU)
- (currently in reserve)
- 89Zr-B.20
- 18F-Rhodamine (proprietary preparation under development – Boston Children’s Hospital)